The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely defined meanings to describe all aspects of how investigations in the biological and medical domains are conducted. OBI re-uses ontologies that provide a representation of biomedical knowledge from the Open Biological and Biomedical Ontologies (OBO) project and adds the ability to describe how this knowledge was derived. We here describe the state of OBI and several applications that are using it, such as adding semantic expressivity to (...) existing databases, building data entry forms, and enabling interoperability between knowledge resources. OBI covers all phases of the investigation process, such as planning, execution and reporting. It represents information and material entities that participate in these processes, as well as roles and functions. Prior to OBI, it was not possible to use a single internally consistent resource that could be applied to multiple types of experiments for these applications. OBI has made this possible by creating terms for entities involved in biological and medical investigations and by importing parts of other biomedical ontologies such as GO, Chemical Entities of Biological Interest (ChEBI) and Phenotype Attribute and Trait Ontology (PATO) without altering their meaning. OBI is being used in a wide range of projects covering genomics, multi-omics, immunology, and catalogs of services. OBI has also spawned other ontologies (Information Artifact Ontology) and methods for importing parts of ontologies (Minimum information to reference an external ontology term (MIREOT)). The OBI project is an open cross-disciplinary collaborative effort, encompassing multiple research communities from around the globe. To date, OBI has created 2366 classes and 40 relations along with textual and formal definitions. The OBI Consortium maintains a web resource providing details on the people, policies, and issues being addressed in association with OBI. (shrink)

Biological ontologies are used to organize, curate, and interpret the vast quantities of data arising from biological experiments. While this works well when using a single ontology, integrating multiple ontologies can be problematic, as they are developed independently, which can lead to incompatibilities. The Open Biological and Biomedical Ontologies Foundry was created to address this by facilitating the development, harmonization, application, and sharing of ontologies, guided by a set of overarching principles. One challenge in reaching these goals was that the (...) OBO principles were not originally encoded in a precise fashion, and interpretation was subjective. Here we show how we have addressed this by formally encoding the OBO principles as operational rules and implementing a suite of automated validation checks and a dashboard for objectively evaluating each ontology’s compliance with each principle. This entailed a substantial effort to curate metadata across all ontologies and to coordinate with individual stakeholders. We have applied these checks across the full OBO suite of ontologies, revealing areas where individual ontologies require changes to conform to our principles. Our work demonstrates how a sizable federated community can be organized and evaluated on objective criteria that help improve overall quality and interoperability, which is vital for the sustenance of the OBO project and towards the overall goals of making data FAIR. Competing Interest StatementThe authors have declared no competing interest. (shrink)

We suggest that the emerging field of the conservation humanities can play a valuable role in biodiversity protection in Papua New Guinea (PNG), where most land remains under collective customary clan ownership. As a first step to mobilising this scholarly field in PNG and to support capacity development for PNG humanities academics, we conducted a landscape review of PNG humanities teaching and research relating to biodiversity conservation and customary land rights. We conducted a systematic literature review, a PNG teaching programme (...) review, and a series of online workshops between the authors (10 PNG-based, 7 UK-based). We found a small but notable amount of PNG research and teaching focused on biodiversity conservation or customary land rights. This included explicit discussion of these topics in 8 of 156 PNG-authored humanities texts published 2010-2020 and related teaching content in the curricula of several different humanities-based programmes. We discuss current barriers to PNG academic development. The growth of fully fledged in-country conservation humanities will require a joint collaborative effort by PNG researchers, who are best placed to carry out such work, and researchers from abroad who can access resources to support the process. (shrink)

I begin, haltingly, and the individual begins, for John Stuart Mill, with an impulse. My impulse, in terms of Mill, is to ask after power and energy in his On Liberty. There, impulses are desires and those of the “Strong” variety are synonymous with energy (Mill 2002, p. 62). An individual with their own impulses has character and one with strong impulses governed by a strong will has energetic character. One without them has no character. I begin haltingly, in (...) part, because, insofar as my impulse is directed toward power and energy, I am unsure as to the will that may or may not govern it, whether this question reveals or begins to reveal something of my character, its degree of energy, or the lack thereof. What does it mean, in other words, to ask about power and energy in this book? Call this question the opening of an experiment in thinking. (shrink)

Interoperability across data sets is a key challenge for quantitative histopathological imaging. There is a need for an ontology that can support effective merging of pathological image data with associated clinical and demographic data. To foster organized, cross-disciplinary, information-driven collaborations in the pathological imaging field, we propose to develop an ontology to represent imaging data and methods used in pathological imaging and analysis, and call it Quantitative Histopathological Imaging Ontology – QHIO. We apply QHIO to breast cancer hot-spot detection with (...) the goal of enhancing reliability of detection by promoting the sharing of data between image analysts. (shrink)

J. L. Schellenberg's Philosophy of Religion argues for a specific brand of sceptical religion that takes ‘Ultimism’ – the proposition that there is a metaphysically, axiologically, and soteriologically ultimate reality – to be the object to which the sceptical religionist should assent. In this article I shall argue that Ietsism – the proposition that there is merely something transcendental worth committing ourselves to religiously – is a preferable object of assent. This is for two primary reasons. First, Ietsism is far (...) more modest than Ultimism; Ietsism, in fact, is open to the truth of Ultimism, while the converse does not hold. Second, Ietsism can fulfil the same criteria that compel Schellenberg to argue for Ultimism. (shrink)

ABSTRACT: So far in this book, we have examined algorithmic decision systems from three autonomy-based perspectives: in terms of what we owe autonomous agents (chapters 3 and 4), in terms of the conditions required for people to act autonomously (chapters 5 and 6), and in terms of the responsibilities of agents (chapter 7). -/- In this chapter we turn to the ways in which autonomy underwrites democratic governance. Political authority, which is to say the ability of a government to exercise (...) power, may be justifiable or not. Whether it is justified and how it can come to be justified is a question of political legitimacy. Political legitimacy is another way in which autonomy and responsibility are linked. This relationship is the basis of the current chapter, and it is important in understanding the moral salience of algorithmic systems. We will draw the connection as follows. We begin, in section 8.1, by describing two uses of technology: crime predicting technology used to drive policing practices and social media technology used to influence elections (including by Cambridge Analytica and by the Internet Research Agency). In section 8.2 we consider several views of legitimacy and argue for a hybrid version of normative legitimacy based on one recently offered by Fabienne Peter. In section 8.3 we will explain that the connection between political legitimacy and autonomy is that legitimacy is grounded in legitimating processes, which are in turn based on autonomy. Algorithmic systems—among them PredPol and the Cambridge Analytica-Facebook-Internet Research Agency amalgam—can hinder that legitimation process and conflict with democratic legitimacy, as we argue in section 8.4. We will conclude by returning to several cases that serve as through-lines to the book: Loomis, Wagner, and Houston Schools. -/- The link below is to an open-access copy of the chapter. (shrink)

This article responds to four critics of Democracy in Spite of the Demos and reiterates its central thesis. Christopher Holman and Théophile Pénigaud attempt to maintain the critical value of democracy by invoking different elements of the deliberative tradition, while Benjamin Schupmann answers my charges by appealing to a strong liberal constitutionalism. I argue that these attempts repeat the ambivalence described and criticized in the book: democracy is taken as an end in itself, but with asterisks that introduce conditions and (...) qualifications. As long as democracy is only desirable given certain caveats, the critical weight is placed on these caveats and not on the figure of democracy. Andrew Norris takes a different approach, interrogating the book’s use of ideology critique and the concept of “socially necessary delusion.” This intervention presents difficulties to the concluding suggestion of the book, but I maintain that that these difficulties can be productive and generative rather than limiting or prohibitive. (shrink)

Wittgenstein’s comment that what can be shown cannot be said has a special resonance with visual representations of power in both Heavy Metal and Fundamentalist Christian communities. Performances at metal shows, and performances of ‘religious theatre’, share an emphasis on violence and destruction. For example, groups like GWAR and Cannibal Corpse feature violent scenes in stage shows and album covers, scenes that depict gory results of unrestrained sexuality that are strikingly like Halloween ‘Hell House’ show presented by neo-Conservative, Fundamentalist (...) Christian churches in the southeastern United States’ ‘Bible Belt’. One group may claim to celebrate violence, the other sees violence as a tool to both encourage ‘moral’ behaviour, and to show that the Christian church is able to ‘speak the language’ of young people who are fans of metal, gore, and horror. Explicit violence, in each case, signifies power relationships that are in transformation. Historically, medieval morality plays and morality cycles had been used as a pedagogical tool. In the modern-day context of fundamentalist religious education, these Hell House performances seek to exclude outsiders and solidify teen membership in the Christian community. Hell House performances are marketed to the young church members, and are seen as a way to reinvigorate conservative Fundamentalist Christianity. Women and girls routinely take part in, and often organize Hell House events. In the context of heavy metal, violent performances do not seek to exclude, but provide an outlet for a variety of socially unacceptable or unpopular feelings. In each context there is an apparent, if not actual, empowering of women who are willing to play particular kinds of roles. The use of violence and gore has a value beyond merely shocking the audience, it is arguably a way that some women find their voice, both for fundamentalist Christians and fundamentalist gore metal fans. (shrink)

This paper considers two competing views of the relationship between preference and desire. On what I call the “preference-first view,” preference is our most basic form of conative attitude, and desire reduces to preference. This view is widely assumed, and essentially treated as orthodoxy, among standard decision theorists, economists, and others. I argue, however, that the preference-first view has things the wrong way around. I first show that the standard motivation offered for this view—motivation underlying foundational work in decision theory (...) and economics—leaves the view with unacceptable psychological implications. I then introduce an alternative view—the “desire-first view”—on which desire is our most basic form of conative attitude, and preference reduces to desire. On the desire-first view I propose, preferences, as comparisons, are best understood as comparisons of the extents to which alternatives are desired. I show that this desire-first view is simple, ecumenical, and explanatorily powerful. (shrink)

In fragment B 12 Anaxagoras asserted: ‘And [Mind] has every gnômê concerning everything and is strong to the greatest degree.’ The definitions of gnômê given in the standard Greek lexicon cover a wide range: ‘mark’, ‘token’, ‘intelligence’, ‘thought’, ‘judgment’, ‘understanding’, ‘attention’, ‘conscience’, ‘reason’, ‘will’, ‘disposition’, ‘inclination’, ‘purpose’, ‘initiative’, ‘opinion’, ‘verdict’, ‘decision’, ‘proposition’, ‘resolution’, ‘advice’, and ‘maxim’. Taking a clue from the assonance of ischei (has) with ischuei (is strong), it would be natural to take both parts of the assertion to (...) be concerned with the extent of Mind’s strength, and this would suggest the translation: ‘for it holds every decision concerning everything and (thereby) has the greatest strength’. So understood, both parts of the assertion would be reinforcing Anaxagoras’ basic claim that Mind ‘rules over’ (kratein) everything. Thus, what Anaxagoras’ cosmic nous does is provide just the kind of intelligent oversight nous typically provides in early Greek poetry and philosophy. (shrink)

In this paper we suggest a revisionist perspective on two significant figures in early modern life science and philosophy: William Harvey and John Locke. Harvey, the discoverer of the circulation of the blood, is often named as one of the rare representatives of the ‘life sciences’ who was a major figure in the Scientific Revolution. While this status itself is problematic, we would like to call attention to a different kind of problem: Harvey dislikes abstraction and controlled experiments (aside from (...) the ligature experiment in De Motu Cordis), tends to dismiss the value of instruments such as the microscope, and emphasizes instead the privileged status of ‘observed experience’. To use a contemporary term, Harvey appears to rely on, and chiefly value, ‘tacit knowledge’. Secondly, Locke’s project is often explained with reference to the image he uses in the Epistle to the Reader of his Essay, that he was an “underlabourer” of the sciences. In fact, despite the significant medical phase of his career, Locke’s ‘empiricism’ turns out to be above all a practical (i.e. ‘moral’) project, which focuses on the delimitation of our powers in order to achieve happiness, and rejects the possibility of naturalizing knowledge. When combined, these two cases suggest a different view of some canonical moments in early modern natural philosophy. (shrink)

The Golden Rule (“what you want done [or not done] to yourself, do [or don’t do] to others”) is the most widely accepted summary statement of human morality, and even today it continues to have philosophical supporters. This article argues that the Golden Rule suffers from four faults, the first two related to the ethics of justice and the second two related to the ethics of benevolence. One, it fails to explain how to deal with non-reciprocation. Two, it fails to (...) make clear that my obligations are obligations regardless of how I would wish to be treated by others. Three, it lacks any special value in explaining the right occasions for benevolence. And, four, it has no power to motivate benevolence. (shrink)

Questions of privacy have become particularly salient in recent years due, in part, to information-gathering initiatives precipitated by the 2001 World Trade Center attacks, increasing power of surveillance and computing technologies, and massive data collection about individuals for commercial purposes. While privacy is not new to the philosophical and legal literature, there is much to say about the nature and value of privacy. My focus here is on the nature of informational privacy. I argue that the predominant accounts of (...) privacy are unsatisfactory and offer an alternative: for a person to have informational privacy is for there to be limits on the particularized judgments that others are able to reasonably make about that person. (shrink)

Mathematicians often speak of conjectures as being confirmed by evidence that falls short of proof. For their own conjectures, evidence justifies further work in looking for a proof. Those conjectures of mathematics that have long resisted proof, such as the Riemann hypothesis, have had to be considered in terms of the evidence for and against them. In recent decades, massive increases in computer power have permitted the gathering of huge amounts of numerical evidence, both for conjectures in pure mathematics (...) and for the behavior of complex applied mathematical models and statistical algorithms. Mathematics has therefore become (among other things) an experimental science (though that has not diminished the importance of proof in the traditional style). We examine how the evaluation of evidence for conjectures works in mathematical practice. We explain the (objective) Bayesian view of probability, which gives a theoretical framework for unifying evidence evaluation in science and law as well as in mathematics. Numerical evidence in mathematics is related to the problem of induction; the occurrence of straightforward inductive reasoning in the purely logical material of pure mathematics casts light on the nature of induction as well as of mathematical reasoning. (shrink)

Review of Searching Eyes: Privacy, the State, and Disease Surveillance in America – By Amy L. Fairchild, Ronald Bayer, and James Colgrove.

This article examines Nietzsche’s enduring influence on Deleuze by showing how the interpretation advanced in Nietzsche and Philosophy informs Deleuze’s later work with Guattari. I analyse Deleuze’s reading of the will to power as a typology of forces and his interpretation of the Overman as a pinnacle of creative activity with an eye towards demonstrating that these are not merely Deleuzian creations but are also defensible interpretations of Nietzsche; and I suggest how these portions of Deleuze’s reading of Nietzsche (...) influence his concepts of desiring-production and nomadism, respectively. By analysing Deleuze’s relation to Nietzsche as a longue durée, we can better appreciate how Deleuze’s early reading of Nietzsche is carried forward in his later work. (shrink)

In his Treatise of Human Nature Hume argues for a provocative account of the soul; the soul - or self, as he prefers to call it - is nothing but a bundle of perceptions. But this bold thesis, concedes Hume, gives rise to a predicament concerning two incompatible propositions, or principles as he calls them: one on the nature of perceptions, the other on the capabilities of the mind: "In short, there are two principles, which I cannot render consistent; nor (...) is it in my power to renounce either of them, viz. that all our distinct perceptions are distinct existences, and that the mind never perceives any real connexion among distinct existences". But the situation is not hopeless, thinks Hume. Someone might be able to show that these principles are actually consistent: "Others, perhaps, or myself, upon more mature reflection, may discover some hypothesis, that will reconcile those contradictions". (Treatise 636, my emphasis) My paper is an attempt to throw light on this important component in Hume’s analysis of his account of the self. In the course of our investigation of Hume's suggestion that an hypothesis can resolve his contradiction we will learn more about his conception of a contradiction - ultimately enriching our understanding of his account of the soul. (shrink)

This essay provides a novel argument for impurism, the view that certain non-truth-relevant factors can make a difference to a belief's epistemic standing. I argue that purists, unlike impurists, are forced to claim that certain ‘high-stakes’ cases rationally require agents to be akratic. Akrasia is one of the paradigmatic forms of irrationality. So purists, in virtue of calling akrasia rationally mandatory in a range of cases with no obvious precedent, take on a serious theoretical cost. By focusing on akrasia, and (...) on the nature of the normative judgments involved therein, impurists gain a powerful new way to frame a core challenge for purism. They also gain insight about the way in which impurism is true: my argument motivates the claim that there is moral encroachment in epistemology. (shrink)

A common response to radical skeptical challenges to our knowledge of the external world has been that there are explanatory reasons (e.g., simplicity, coherence, explanatory power, conservatism) for favoring commonsense explanations of our sensory experiences over skeptical explanations. Despite the degree of visibility this class of response has enjoyed, it has often been viewed with skepticism [sic] by the epistemological community because of concerns about the epistemic merits of explanatory reasoning. I argue that skeptical challenges that employ skeptical hypotheses (...) presuppose central explanationist tenets and that this fact should raise one’s estimation of the strength of explanationist responses to skepticism. (shrink)

There are spells in the Greek and Demotic Magical Papyri which promise divine visitations, assistants, ecstatic states, vessel inquiries, and vivid dreams. They also require powerful psychoactive botanical ingredients. How did these spells work and what were the expectations of somebody purchasing them? Looking at the ingredients of visionary spells and relying on the pharmacology of Dioscorides and Theophrastus, I ascertain how these spells achieved the promised visions and altered states of consciousness for the user. These spells guarantee great spiritual (...) and recreational entertainment to the client who would need an abundance of money to purchase the ingredients. (shrink)

This work has two major goals. The first is to reframe the problem of political authority from its Conservative framing to a Reformist framing. This change creates a new benchmark for the success of a theory. Rather than justifying a pre-existing intuition, a theory can be successful if it could establish political authority whenever the state itself or an individual’s relationship to it changes. This change also shifts the focus from the state’s right to rule to moral housekeeping. In other (...) words, the main goal is not to see when the state can use coercion against its citizens but rather to determine what political obligations citizens could have under different scenarios so that citizens can more accurately keep track of their moral reasons for action. The second major goal is to call into question epistemic theories of democratic authority through a critical examination of David Estlund’s theory of normative consent. Normative consent cannot establish political authority. Even granting that it could, normative consent would bind individuals to epistemic procedures rather than democratic procedures given that epistemic procedures better solve the moral problems that generate normative consent. However, this then raises worries from the public reason perspective that epistemic procedures would impose a procedure on some citizens which they could reject from a qualified position. To overcome this worry, it is shown that epistemic procedures based on reducing the power of the ignorant rather than raising the power of the experts are not open to such qualified rejection, and democratic procedures in the real world will do no better than a coin flip at selecting correct policies. In the end, one branch of epistemic conceptions of democratic authority are proven untenable. (shrink)

Children continue to be overlooked as a topic of concern in discussions around the ethical use of people’s data and information. Where children are the subject of such discussions, the focus is often primarily on privacy concerns and consent relating to the use of their data. This paper highlights the unique challenges children face when it comes to online interferences with their decision-making, primarily due to their vulnerability, impressionability, the increased likelihood of disclosing personal information online, and their developmental capacities. (...) These traits allow for practices such as hypernudging to be executed on them more accurately and with more serious consequences, specifically by potentially undermining their autonomy. We argue that children are autonomous agents in the making and thus require additional special protections to ensure that the development of their autonomy is safeguarded. This means that measures should be taken to prohibit most forms of hypernudging children and thus ensure that they are protected from this powerful technique of digital manipulation. (shrink)

The chapter examines fifty years of philosophers working on lying - from the 1970s to the current day – focusing on how lying is defined (descriptively and normatively), whether lying involves an intention to deceive (Deceptionists) or not (Non-Deceptionists), why lying is wrong, and whether lying is worse than other forms of deception, including misleading with the truth. Philosophers discussed include Roderick Chisholm and Thomas Feehan, Alan Donagan, Sissela Boy, Charles Fried, David Simpson, David Simpson, Bernard Williams, Paul Faulkner, (...) Thomas Carson, Roy Sorensen, Don Fallis, Jennifer Saul, Andreas Stoke, Jonathan Webber and Clea Rees. (shrink)

It has become orthodox to read Nietzsche as proposing the ‘sublimation’ of troublesome behavioural impulses. On this interpretation, he is said to denigrate the elimination of our impulses, preferring that we master them by pressing them into the service of our higher goals. My thesis is that this reading of Nietzsche’s conception of self-cultivation does not bear scrutiny. Closer examination of his later thought reveals numerous texts that show him explicitly recommending an eliminatory approach to self-cultivation. I invoke his theory (...) of the will to power in order to explain why he persistently valorises both elimination and sublimation as preconditions of healthy subjective unity. I conclude that which of these two approaches he recommends in a given situation depends on whether or not the impulse in question can be put to use within the overall economy of our drives. (shrink)

Catholic integralism is a tradition of thought which insists upon the ideal nature of political arrangements on which the Church can mandate the State to advance the supernatural good of the baptized. Thomas Pink, one of the foremost defenders, has proposed controversially that these arrangements are ideal because the Church possesses rights to civil coercive authority. But I argue this fact would not entail – by itself – the ideal nature of those arrangements. To the contrary, I argue that integralism (...) is unjust, even assuming Pink’s claims are true. The integralist ideal necessarily involves violating moral duties toward unbaptized citizens. Integralism does so in imposing differential civic burdens upon baptized/unbaptized citizens and in implying that non-Catholics might be rightly excluded from power merely on account of religious beliefs, both without just cause. I conclude by showing that readings of the relevant Catholic teaching can be given which are non-integralist. (shrink)

Ancient Chinese and Greek thinkers alike were preoccupied with the moral value of music; they distinguished between good and bad music by looking at the music’s effect on moral character. The idea can be understood in terms of two closely related questions. Does music have the power to affect the ethical character of either listener or performer? If it does, is it better as music for doing so? I argue that an affirmative answers to both questions are more plausible (...) than it might seem at first. (shrink)

This paper interprets the influential colony management simulator ‘Dwarf Fortress’ existentially, in terms of finitude, absurdity, and narrative. It applies Aarseth/Möring’s proposed method of game interpretation, adopting their definition of ‘cybermedia’ as a generalized game ontology, then providing a specialized ontology of ‘Dwarf Fortress’ which describes its genre and salient gameplay features, incorporating Ian Bogost’s concept of ‘procedural rhetoric’. It then gives an existentialist interpretation of ‘Dwarf Fortress’ which centres on ‘finitude’, ‘absurdity’, and ‘narrative’, showing that ‘Dwarf Fortress’ is a (...) game about the existential tensions involved in being human. We live knowing our lives and civilizations are finite, that there are radical limits on what we can know and do. There is no meaning inherent in the world, or in history, so it is up to us to create our own, and one of our most powerful ways of doing this is narrative. (shrink)

I reconcile the spatiotemporal location of repeatable artworks and impure sets with the non-location of natural numbers despite all three being varieties of abstract objects. This is possible because, while the identity conditions for all three can be given by abstraction principles, in the former two cases spatiotemporal location is a congruence for the equivalence relation featuring in the relevant principle, whereas in the latter it is not. I then generalize this to other ‘physical’ properties like shape, mass, and causal (...) powers. (shrink)

The Early Han enjoyed some prosperity while it struggled with centralization and political control of the kingdom. The Later Han was plagued by the court intrigue, corrupt eunuchs, and massive flooding of the Yellow River that eventually culminated in popular uprisings that led to the demise of the dynasty. The period that followed was a renewed warring states period that likewise stimulated a rebirth of philosophical and religious debate, growth, and innovations. Alan K. L. Chan and Yuet-Keung Lo's Philosophy (...) and Religion in Early Medieval China is a welcome addition to the growing body of literature on medieval China. It is a companion volume to their coauthored work, Interpretation and Literature in Early .. (shrink)

Pascal’s Wager does not exist in a Platonic world of possible gods, abstract probabilities and arbitrary payoffs. Real decision-makers, such as Pascal’s “man of the world” of 1660, face a range of religious options they take to be serious, with fixed probabilities grounded in their evidence, and with utilities that are fixed quantities in actual minds. The many ingenious objections to the Wager dreamed up by philosophers do not apply in such a real decision matrix. In the situation Pascal addresses, (...) the Wager is a good bet. In the situation of a modern Western intellectual, the reasoning of the Wager is still powerful, though the range of options and the actions indicated are not the same as in Pascal’s day. (shrink)

I begin by arguing that, for Kant, the pure category of substance has both a general content that is in play whenever we think of any entity as a substance as well as a more specific content that arises in conjunction with the thought of what Kant calls a positive noumenon. Drawing on this new “Dual Content” account of the pure category of substance, I offer new answers to two contested questions: What is the relation of the pure category to (...) phenomenal substance? What, if any, epistemic gains can we achieve when we apply the pure category to noumena? Regarding the first question, I argue that while phenomenal substance does not qualify as a substance according to the Inner-Simple Conception, it does qualify as one according to the Subsistence-Power Conception. Regarding the second question, I argue that, in the case of the substantiality of positive noumena, Kant’s account allows for justified conditional beliefs involving the Inner-Simple Conception. In the case of negative noumena, it allows for justified existential beliefs involving the Subsistence-Power Conception. (shrink)

Though there is no international government, there are many international regimes that enact binding regulations on particular matters. They include the Basel II regime in banking, IFRS in accountancy, the FIRST computer incident response system, the WHO’s system for containing global epidemics and many others. They form in effect a very powerful international public sector based on technical expertise. Unlike the public services of nation states, they are almost free of accountability to any democratically elected body or to any legal (...) system. Although by and large they have acted for good, the dangers of long-term unaccountability are illustrated by the travesties of justice perpetrated by the International Labour Organisation Administrative Tribunal. (shrink)

“Physical premotion” is a concept associated with Baroque Catholic theological debates concerning grace and freedom. In this paper, I present an argument that the entities identified in this debate, physical premotions, are necessary for any classical theist’s account of divine causality. A “classical theist” is a theist who holds both that God is simple, that is, without inhering properties, and that humans and God are both free in the incompatibilist sense. In fact, not only does the acceptance of physical premotions (...) not entail determinism, physical premotions are the only way for classical theists to preserve the aforementioned two commitments. Nevertheless, the theory of premotions cannot help theologians resolve questions of how God causes human free acts without violating their freedom. (shrink)

Among worldviews, in addition to the options of materialist atheism, pantheism and personal theism, there exists a fourth, “local emergentism”. It holds that there are no gods, nor does the universe overall have divine aspects or any purpose. But locally, in our region of space and time, the properties of matter have given rise to entities which are completely different from matter in kind and to a degree god-like: consciousnesses with rational powers and intrinsic worth. The emergentist option is compared (...) with the standard alternatives and the arguments for and against it are laid out. It is argued that, among options in the philosophy of religion, it involves the minimal reworking of the manifest image of common sense. Hence it deserves a place at the table in arguments as to the overall nature of the universe. (shrink)

Compartmentalizing our distinct personal identities is increasingly difficult in big data reality. Pictures of the person we were on past vacations resurface in employers’ Google searches; LinkedIn which exhibits our income level is increasingly used as a dating web site. Whether on vacation, at work, or seeking romance, our digital selves stream together. One result is that a perennial ethical question about personal identity has spilled out of philosophy departments and into the real world. Ought we possess one, unified identity (...) that coherently integrates the various aspects of our lives, or, incarnate deeply distinct selves suited to different occasions and contexts? At bottom, are we one, or many? The question is not only palpable today, but also urgent because if a decision is not made by us, the forces of big data and surveillance capitalism will make it for us by compelling unity. Speaking in favor of the big data tendency, Facebook’s Mark Zuckerberg promotes the ethics of an integrated identity, a single version of selfhood maintained across diverse contexts and human relationships. This essay goes in the other direction by sketching two ethical frameworks arranged to defend our compartmentalized identities, which amounts to promoting the dis-integration of our selves. One framework connects with natural law, the other with language, and both aim to create a sense of selfhood that breaks away from its own past, and from the unifying powers of big data technology. (shrink)

‘Of Ephesus’ begins with a series of vivid impressions of a wild and free nature—vineyards rolling across the landscape, an untrammeled sky, a runaway donkey, flaming pinecones, roosters, and colorful kites and flags. Fire in some form (wildfires, the sun, flames, torches, lightning, sunlight) is the hallmark of a dynamic reality. The reference to ‘St. Heraclitus’ supports this interpretation: Elytis, like Heraclitus, seeks to alert his audience to the possible existence of a higher realm of being. So he fashions a (...) series of striking juxtapositions intended to disrupt our ordinary experience of the world and to spark a vision of an alternative reality. In the process he draws on Heraclitus’ doctrine of the unity of the opposites, on the conception of fire as the basic power that rules the cosmos, and on the conviction that beyond the world we know through ordinary sense experience lies a second, higher reality. (shrink)

Cells are cognitive entities possessing great computational power. DNA serves as a multivalent information storage medium for these computations at various time scales. Information is stored in sequences, epigenetic modifications, and rapidly changing nucleoprotein complexes. Because DNA must operate through complexes formed with other molecules in the cell, genome functions are inherently interactive and involve two-way communication with various cellular compartments. Both coding sequences and repetitive sequences contribute to the hierarchical systemic organization of the genome. By virtue of nucleoprotein (...) complexes, epigenetic modifications, and natural genetic engineering activities, the genome can serve as a read-write storage system. An interactive informatic conceptualization of the genome allows us to understand the functional importance of DNA that does not code for protein or RNA structure, clarifies the essential multidirectional and systemic nature of genomic information transfer, and emphasizes the need to investigate how cellular computation operates in reproduction and evolution. (shrink)

In this essay, I review in great detail Ian Garden’s outstanding book, The Third Reich’s Celluloid War. Garden begins by discussing propaganda theory and then discusses not just Nazi feature films and documentaries, but television as well. (The Nazis had the earliest TV network). All in all, the regime produced over 1,300 feature films during its time in power. Garden also compares Nazi propaganda films to British and American ones.

Software application ontologies have the potential to become the keystone in state-of-the-art information management techniques. It is expected that these ontologies will support the sort of reasoning power required to navigate large and complex terminologies correctly and efficiently. Yet, there is one problem in particular that continues to stand in our way. As these terminological structures increase in size and complexity, and the drive to integrate them inevitably swells, it is clear that the level of consistency required for such (...) navigation will become correspondingly difficult to maintain. While descriptive semantic representations are certainly a necessary component to any adequate ontology-based system, so long as ontology engineers rely solely on semantic information, without a sound ontological theory informing their modeling decisions, this goal will surely remain out of reach. In this paper we describe how Language and Computing nv (L&C), along with The Institute for Formal Ontology and Medical Information Sciences (IFOMIS), are working towards developing and implementing just such a theory, combining the open software architecture of L&C’s LinkSuiteTM with the philosophical rigor of IFOMIS’s Basic Formal Ontology. In this way we aim to move beyond the more or less simple controlled vocabularies that have dominated the industry to date. (shrink)

The question of the imagination is rather like the question Augustine raised with regard to the nature of time. We all seem to know what it involves, yet find it difficult to define. For Descartes, the imagination was simply our faculty for producing a mental image. He distinguished it from the understanding by noting that while the notion of a thousand sided figure was comprehensible—that is, was sufficiently clear and distinct to be differentiated from a thousand and one sided figure—the (...) figure could not be clearly pictured in our mind. The representation of its sides exceeded our powers of imagination.[i] This view of the imagination as our ability to produce a mental image fails, however, to distinguish it from remembering. Let us say that I see an object and then I close my eyes, maintaining the image of the object. Is this imagining or short term memory? What about the case when I recall this image an hour later? Am I imagining or remembering it? Such examples make it clear that imagination, as distinct from memory, implies something more than the ability to produce a mental image. It involves, as Sartre pointed out, a certain attitude towards this image. Engaging in it, we deny its reality. In Sartre’s words, imagination “carries within it a double negation; first, it is the nihilation of the world (since the world is not offering the imagined object as an actual object of perception), secondly, the nihilation of the object of the image (it is posited as not actual) ...” (BN, p. 62). Imagination, then, represents the imagined as nonactual. (shrink)

There is a general presumption against arming outlaw states. But can that presumption sometimes be overturned? The argument considered here maintains that outlaw states can have legitimate security interests and that transferring weapons to these states can be an appropriate way of promoting those interests. Weapons enable governments to engage in wrongful oppression and aggression, but they also enable them to fend off predators in a manner that can be beneficial to their citizens. It clearly does not follow from the (...) fact that a state is oppressive or aggressive that it will never be a victim of wrongful aggression itself, and while an outlaw state’s primary aim in repelling such aggression will often be the preservation of its own power, its defensive manoeuvres will sometimes also serve its citizens’ interests. In short, supplying weapons to outlaw states may sometimes contribute to the protection of innocents. (shrink)

This paper argues that Foucault’s The History of Sexuality contains an implicit but important interpretation of Nietzsche’s critique of the ‘ascetic ideal’. It suggests that Foucault undertakes a non-reductive synthesis of seemingly conflicting aspects of Nietzsche’s thought, on the one hand, its valorisation of the ‘Dionysian’ and, on the other hand, its enthusiasm for ‘self-disciplining’. The consequences of a failure to appreciate how Nietzsche’s thought combines these two themes is illustrated through a sketch of what is termed an ‘oppositional’ interpretation (...) of his thought. This erroneously imposes the nature/culture distinction upon Nietzsche’s thought and reads its critique of morality in terms of ‘repression’, the ‘renunciation of instinct’ etc. An alternative, ‘economic’ interpretation of Nietzsche’s thought in which his ‘affirmation of the Dionysian’ and valorisation of self-disciplining are conjoined is outlined and recommended. Foucault’s interpretation of Nietzsche is presented as an example of such an ‘economic’ reading, in that it appreciates Nietzsche’s libidinal interpretation of self-denial. This combination of Nietzsche’s and Foucault’s thought is termed ‘noble ascesis’. This is illustrated through a reading of Foucault’s account of Greco-Roman ethics. Attention is drawn to how Foucault’s implicit interpretation of Nietzsche helps to clarify Nietzsche’s conception of the possibility of a ‘healthy’ appropriation of the ‘ascetic ideal’. The paper attempts to show how the ‘non-moral’ ethical practice Foucault retrieves from the classical world, on the basis of Nietzsche’s distinction between different forms of self-denial, emphasises the affective and libidinal investments of asceticism. This, in turn, is related to Foucault’s critique of the ‘repressive hypothesis’ and overcoming of the ‘repression/transgression’ model of the nature of power. However, the paper identifies some tensions between Nietzsche’s and Foucault’s accounts of asceticism and interpretations of the ethical practice of the Greco-Roman world and closes by considering whether or not these tensions can be resolved. (shrink)

Xenophanes of Colophon (fl. 530 BC) is widely regarded as the first skeptic in the history of Western philosophy, but the character of his skepticism as expressed in his fragment B 34 has long been a matter of debate. After reviewing the interpretations of B 34 defended by Hermann Fränkel, Bruno Snell, and Sir Karl Popper, I argue that B 34 is best understood in connection with a traditional view of the sources and limits of human understanding. If we hold (...) that mortal beings can achieve certain knowledge only with the assistance of divine powers, while rejecting any possibility of bridging the divine-human gap, a broad skepticism concerning the prospects for human knowledge becomes inevitable. It is therefore of some relevance that Xenophanes repudiated the practice of divination through signs (mantikê) and offered entirely naturalistic explanations of phenomena popularly regarded as indications of the divine will (thunder, lightning, eclipses, rainbows, etc.). (shrink)

Stretching is one of the important things to do before doing a physical activity. Stretching helps you to avoid possible injuries, muscle soreness and even improve overall performance. The researcher came up with an idea to create a modified stretching routine to assess if our created modified stretching is better than the traditional stretching. This study aims to assess the impact or the effect of the created modified stretching routine to the performance of students. This study utilizes the quasi-experimental research (...) design. In analyzing the data, descriptive statistics and multiple linear regression are being utilized. Overall, based on the results, utilizing modified stretching routine has a positive impact to the student’s performance. There is a significant difference on the student’s performance when they use the modified stretching routine than the traditional stretching routine. From the data collected, it shows that students who uses the modified stretching routine definitely improve their flexibility, cardiovascular endurance and muscular endurance. (shrink)

Western philosophy begins with Thales, Anaximander, and Anaximenes. Or so we are told by Aristotle and many members of the later doxographical tradition. But a good case can be made that several centuries before the Milesian thinkers began their investigations, the poets of archaic Greece reflected on the limits of human intelligence and concluded that no mortal being could know the full and certain truth. Homer belittled the mental capacities of ‘creatures of a day’ and a series of poets of (...) the archaic period declared that mortals think only in terms of ‘what they meet with’ while failing to detect the larger cycles that make for success or failure. While Xenophanes embraced this pessimistic tradition, a number of early thinkers (Heraclitus, Parmenides, Empedocles, and Philolaus) expressed a more positive view of the powers of human intelligence, at least in those who heard and took to heart their novel philosophical teachings. (shrink)

• It would be a moral disgrace for God (if he existed) to allow the many evils in the world, in the same way it would be for a parent to allow a nursery to be infested with criminals who abused the children. • There is a contradiction in asserting all three of the propositions: God is perfectly good; God is perfectly powerful; evil exists (since if God wanted to remove the evils and could, he would). • The religious believer (...) has no hope of getting away with excuses that evil is not as bad as it seems, or that it is all a result of free will, and so on. Piper avoids mentioning the best solution so far put forward to the problem of evil. It is Leibniz’s theory that God does not create a better world because there isn’t one — that is, that (contrary to appearances) if one part of the world were improved, the ramifications would result in it being worse elsewhere, and worse overall. It is a “bump in the carpet” theory: push evil down here, and it pops up over there. Leibniz put it by saying this is the “Best of All Possible Worlds”. That phrase was a public relations disaster for his theory, suggesting as it does that everything is perfectly fine as it is. He does not mean that, but only that designing worlds is a lot harder than it looks, and determining the amount of evil in the best one is no easy matter. Though humour is hardly appropriate to the subject matter, the point of Leibniz’s idea is contained in the old joke, “An optimist is someone who thinks this is the best of all possible worlds, and a pessimist thinks.. (shrink)

The essential idea of Leibniz’s Theodicy was little understood in his time but has become one of the organizing themes of modern mathematics. There are many phenomena that are possible locally but for purely mathematical reasons impossible globally. For example, it is possible to build a spiral staircase that is rising at any given point, but it is impossible to build one that is rising at all points and comes back to where it started. The necessity is mathematically provable, so (...) not subject to exception by divine power. Leibniz’s Theodicy argues that God could improve the universe locally in many ways, but not globally. This paper defends Leibniz, giving positive reasons for believing that there are so many necessary interconnections between goods and evils that God is faced with a choice like the classic Trolley case, where all of the scenarios that could be chosen upfront contain evils, but some more than others. Local changes for the better seem easy to imagine, but a proper understanding of global constraints undermines the initial impression that they can be done without global cost. The paper concludes by explaining how the context of the Leibnizian argument makes it reasonable to pursue the issue of whether there are no worlds better than this one. (shrink)

Sophocles’ Oedipus the King is an extended meditation on the limits of human intelligence, or more precisely, on how a man renowned for the power of his intellect could fail to know the most important truths. One could argue, however, that Sophocles intended for his audiences to take away a second, narrower lesson: namely that divinely inspired seers such as Tiresias have a surer claim on truth than do those who, like Oedipus, seek to gain knowledge through their own (...) efforts. Thus, the Oedipus can be seen as a defense of prophecy and a reaction against the complex of scientific and philosophical ideas known as “the 5th-century Enlightenment.” I offer some support for this reading of the Oedipus. I also argue that part of the cultural background of the Oedipus consisted of ideas about knowledge introduced into Greek thought by the outspoken critic of Greek popular religion, Xenophanes of Colophon. (shrink)